Neuroinflammation in the Ventral Medial Hypothalamus: Dietary and social influences
Faculty Sponsor(s)
Philip Baker, Ph.D.
Presentation Type
Event
Project Type
Research in progress
Primary Department
Psychology
Description
To study high fat diets and social isolation’s impact on neuroinflammation, 36 rats were divided into four groups: socially isolated with high fat diets, socially isolated with normal chow, socialized with high fat diets, and socialized with normal chow. 40-micron coronal brain slices for each rat were stained with GFAP and IBA1 immunofluorescence stains. Using confocal microscopy to visualize astrocyte expression and microglia morphology and expression, brains will be examined for neuroinflammatory markers. This poster will explore whether high fat, high sugar diets and social isolation have a significant impact on neuroinflammation in the ventral medial hypothalamus.
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Neuroinflammation in the Ventral Medial Hypothalamus: Dietary and social influences
To study high fat diets and social isolation’s impact on neuroinflammation, 36 rats were divided into four groups: socially isolated with high fat diets, socially isolated with normal chow, socialized with high fat diets, and socialized with normal chow. 40-micron coronal brain slices for each rat were stained with GFAP and IBA1 immunofluorescence stains. Using confocal microscopy to visualize astrocyte expression and microglia morphology and expression, brains will be examined for neuroinflammatory markers. This poster will explore whether high fat, high sugar diets and social isolation have a significant impact on neuroinflammation in the ventral medial hypothalamus.
Rights Statement
Comments
Also presented at Erickson Conference, Seattle, WA, May 2025.