Presentation Type
Event
Project Type
Research in progress
Primary Department
Psychology
Description
In this study, we are investigating the effects of MK-801 on male and female Sprague Dawley rats. According to D’Souza et al. (2001), females have a stronger reaction to MK-801 than males. Correspondingly, the current study measures the varied effects of MK-801 on rat models using an optimal decision-making task. The rats are injected with doses of MK-801. Then, they choose between a Fixed-Delay (FD) (ten-second intervals) and a Progressive-Delay (PD) lever (one second progressive increase) to receive rewards. We are currently in the process of obtaining results analyzing the relationship between sex and MK-801’s effects.
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Included in
Relationship between sex and MK801's effects in rats.
In this study, we are investigating the effects of MK-801 on male and female Sprague Dawley rats. According to D’Souza et al. (2001), females have a stronger reaction to MK-801 than males. Correspondingly, the current study measures the varied effects of MK-801 on rat models using an optimal decision-making task. The rats are injected with doses of MK-801. Then, they choose between a Fixed-Delay (FD) (ten-second intervals) and a Progressive-Delay (PD) lever (one second progressive increase) to receive rewards. We are currently in the process of obtaining results analyzing the relationship between sex and MK-801’s effects.
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