Project Title
Localization and initial analysis of MAPK and IP3K-Akt signaling pathways in hemocytes of the pond snail, Lymnaea stagnalis
Document Type
Event
Start Date
10-5-2019 3:30 PM
End Date
10-5-2019 6:30 PM
Description
Recent evidence suggests immune cells (hemocytes) of mollusks utilize several signaling pathways in their active responses to bacterial infections or tissue damage. We have examined the role of two kinases involved in the motility changes associated with such responses: ERK 1/2, a key kinase in the MAPK cascade and Akt, a key kinase in the PI3K pathway. Our hypothesis is that these two pathways act in concert to enable activation of motile phagocytosis.
Discipline
Biology
Research Mentor(s)
Richard L. Ridgway
Copyright Status
http://rightsstatements.org/vocab/InC/1.0/
Additional Rights Information
Copyright held by author(s).
Localization and initial analysis of MAPK and IP3K-Akt signaling pathways in hemocytes of the pond snail, Lymnaea stagnalis
Recent evidence suggests immune cells (hemocytes) of mollusks utilize several signaling pathways in their active responses to bacterial infections or tissue damage. We have examined the role of two kinases involved in the motility changes associated with such responses: ERK 1/2, a key kinase in the MAPK cascade and Akt, a key kinase in the PI3K pathway. Our hypothesis is that these two pathways act in concert to enable activation of motile phagocytosis.
Rights Statement
