Why is pain so subjective?: A study on social isolation & high fat diet in long evans rats Pain sensitivity & neuroinflammation.
Faculty Sponsor(s)
Philip Baker, Ph.D.,Jessica Fossum, Ph.D.,Jenny Lee Vaydich, Ph.D.
Presentation Type
Poster
Project Type
Research in progress
Primary Department
Psychology
Description
This study analyzes the intricate dynamics between social isolation, high-fat diet, and their impact on pain subjectivity and neuroinflammatory parameters in Peri-adolescent rats. It posits that exposure to either social isolation, a high-fat diet, or both during this developmental phase may precipitate heightened pain sensitivity and escalated neuroinflammatory responses. Through pain sensitivity assessments, distinct patterns in pain tolerance across housing conditions emerged, with group-housed cohorts displaying elevated tolerance levels. Subsequent analyses will explore potential modulatory roles of astrocyte and microglia activation on pain perception and regions of the brain associated with sociability.
Copyright Status
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Additional Rights Information
Copyright held by author(s).
Why is pain so subjective?: A study on social isolation & high fat diet in long evans rats Pain sensitivity & neuroinflammation.
This study analyzes the intricate dynamics between social isolation, high-fat diet, and their impact on pain subjectivity and neuroinflammatory parameters in Peri-adolescent rats. It posits that exposure to either social isolation, a high-fat diet, or both during this developmental phase may precipitate heightened pain sensitivity and escalated neuroinflammatory responses. Through pain sensitivity assessments, distinct patterns in pain tolerance across housing conditions emerged, with group-housed cohorts displaying elevated tolerance levels. Subsequent analyses will explore potential modulatory roles of astrocyte and microglia activation on pain perception and regions of the brain associated with sociability.
Rights Statement
