Date of Award
Spring 6-2-2026
Document Type
Honors Project
University Scholars Director
Dr. Joshua Tom
First Advisor/Committee Member
Dr. John Douglass
Keywords
Astrocytes, Neurology, Dorsomedial hypothalamus, Mice
Abstract
The dorsomedial hypothalamus (DMH) region of the brain has been shown to be important for anticipatory feeding activity and play a role in restricting excessive food intake. In obese animals that overconsume calories, astrocytes within the DMH exhibit intracellular signaling changes indicative of cellular activation. Because astrocytes are known to influence neuronal function, we hypothesize that activated astrocytes regulate behavior. In the current study, we use chemogenetics combined with stereotaxic surgery to assess the contribution of astrocyte activity in the DMH towards metabolic behaviors.
Recommended Citation
Lisenby, Bella M., "Activated Dorsomedial Hypothalamic astrocytes regulate feeding behavior" (2026). Honors Projects. 267.
https://digitalcommons.spu.edu/honorsprojects/267
Copyright Status
http://rightsstatements.org/vocab/InC/1.0/
Additional Rights Information
Copyright held by author.
Included in
Endocrinology, Diabetes, and Metabolism Commons, Medical Neurobiology Commons, Neurology Commons, Neurosciences Commons
Comments
A project submitted in partial fulfillment of the requirements of the University Scholars Honors Program.