Sex-Specific neuroinflammatory effects of chronic social isolation and hyper-palatable diet in adolescent rodents
Faculty Sponsor(s)
Philip Baker, Ph.D.,Jessica Fossum, Ph.D.
Presentation Type
Presentation
Project Type
Research in progress
Primary Department
Psychology
Location
the Cascade Room in Upper Gwinn
Description
Literature has supported the impact of both social isolation and exposure to high fat-high sugar (“hyperpalatable”) diets on neuroinflammation and behavior in rats. Historically, these behavioral impacts are shown to differ between the sexes. This ongoing research project seeks to examine the relationship between these variables during peri-adolescence and adult neuroinflammatory responses within brain regions associated with cognition, memory, and behavior. Utilizing immunohistochemical staining of microglia, this study proposes that male and female rats will exhibit key differences in neuroinflammatory response to peri-adolescent stress and hyperpalatable diet.
Copyright Status
http://rightsstatements.org/vocab/InC/1.0/
Additional Rights Information
Copyright held by author(s).
Sex-Specific neuroinflammatory effects of chronic social isolation and hyper-palatable diet in adolescent rodents
the Cascade Room in Upper Gwinn
Literature has supported the impact of both social isolation and exposure to high fat-high sugar (“hyperpalatable”) diets on neuroinflammation and behavior in rats. Historically, these behavioral impacts are shown to differ between the sexes. This ongoing research project seeks to examine the relationship between these variables during peri-adolescence and adult neuroinflammatory responses within brain regions associated with cognition, memory, and behavior. Utilizing immunohistochemical staining of microglia, this study proposes that male and female rats will exhibit key differences in neuroinflammatory response to peri-adolescent stress and hyperpalatable diet.